Searchable abstracts of presentations at key conferences in endocrinology

ea0065p172 | Metabolism and Obesity | SFEBES2019

Physicochemical optimization of dermal insulin patches: effects on selected metabolic parameters in STZ-induced diabetic rats

Mfayela Nokuphiwa , Mabandla Musa , Musabayane Cephas Tagumirwa , Hadebe Silindile Innocentia

Investigations conducted in our laboratory have shown that transdermal delivery of insulin has several potential advantages over the conventional route. These pectin-insulin (PI)-containing dermal patches possess the ability to maintain sustained controlled release of insulin into the bloodstream of streptozotocin-induced diabetic rats with concomitant reduction of blood glucose levels. We have successfully formulated and optimized the concoction of the PI-containing dermal pa...